Research and studies

Research and studies

Research and studies 

This page covers the research work and studies we are currently undertaking which support advances in fertility treatment.

LOCI Study

For more information on the LOCI study, please click here

  • Markers of fertility in seminal plasma study:

Prior to and during fertility treatment, routine analysis looks at the quantity and quality of sperm in semen samples provided by the man as a measure of fertility. However, this investigation examines the fluid which carries the sperm. Research has shown that proteins in this fluid (so-called ‘cytokines’) play a role in preparing the woman’s womb for the embryo to implant. High levels of these cytokines have previously been linked to oxidative stress (oxygen-related damage) in sperm. This can increase sperm DNA damage, resulting in poor fertilization and implantation rates.

This study aims to measure proteins/oxidative stress in semen and blood in men and to assess their relationship with fertility. As such, the study will recruit couples in which men display a range of fertility and sperm characteristics, including pregnancy following fertility treatment.

To discover more about this please see the video below. 

To take part in the study please see this leaflet.